TEDX List of Potential Endocrine Disruptors
The TEDX List of Potential Endocrine Disruptors is a database of chemicals with the potential to affect the endocrine system.
Endocrine effects include not only direct effects on traditional endocrine glands, their hormones and receptors (such as estrogens, anti-androgens, and thyroid hormones), but also all other hormones and signaling cascades that affect the body’s systems and processes, including reproductive function and fetal development, the nervous system and behavior, the immune and metabolic systems, gene expression, the liver, bones, and many other organs, glands and tissues.
Why do we call them potential endocrine disruptors? No one has defined how much scientific evidence is “enough” to call a chemical an endocrine disruptor (witness the ongoing BPA debate). The purpose of the TEDX List is to present the chemicals for which at least one peer-reviewed study has been published, so that scientists, regulators, advocates, and the public are better informed.
To date (June, 2015) there are nearly 1,000 endocrine disruptors on the TEDX List. Chemicals can be searched by full or partial chemical name, by CAS1 number, or by categories derived from the uses and sources of the chemicals.
Every chemical on the TEDX List has one or more verified citations. Each citation is from published, accessible, primary scientific research demonstrating effects on the endocrine system.
References are provided to support each chemical’s inclusion on the list. The number of citations presented in the TEDX List has been limited for practical reasons. It does not reflect the relative amount of research that has been done on each chemical and therefore should not be used as a method of ranking or prioritizing.
The TEDX List is an on-going project. Chemicals will be added as new studies are published and as prior research is identified for endocrine disruptors not on the current list.
1The American Chemical Society has established the Chemical Abstracts Service (CAS) number system to identify unique chemical substances. A single substance can have many different names, but only one CAS number.